Cannabidiol (CBD) Reduces Vomiting and Nausea

Considerable evidence demonstrates that manipulation of the endocannabinoid system reduces nausea and vomiting in humans and other animals.



Regulation of nausea and vomiting by cannabinoids and the endocannabinoid system.
Eur J Pharmacol. 2014 Jan 5;722:134-46. doi: 10.1016/j.ejphar.2013.09.068. Epub 2013 Nov 1.


Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus.
Br J Pharmacol. 2012 Apr;165(8):2620-34. doi: 10.1111/j.1476-5381.2011.01621.x.


Regulation of nausea and vomiting by cannabinoids.
Br J Pharmacol. 2011 Aug;163(7):1411-22. doi: 10.1111/j.1476-5381.2010.01176.x.


Psychopharmacology (Berl). 2011 Jul;216(1):149.
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